Fueling fibrosis in chronic hepatitis C
نویسندگان
چکیده
منابع مشابه
Fueling fibrosis in chronic hepatitis C.
I n the 23 y that have elapsed since the discovery of hepatitis C virus (HCV), many thousands of papers have been published dealing with chronic hepatitis C. Tremendous strides have been made, especially in the development of efficacious antiviral agents that can be administered orally (1). Nonetheless, many gaps remain in our understanding of the disease, and the burden it imposes on the healt...
متن کاملHepatic steatosis and fibrosis in chronic hepatitis C in Taiwan.
Hepatitis C virus (HCV) infection has been associated with hepatic steatosis. However, the role of hepatic steatosis in the pathogenesis of HCV infection remains controversial. In our study, 425 consecutive HCV-viremic patients with biopsy-proven chronic hepatitis C (male, 264; mean age, 49.0 years) were enrolled. Scoring of hepatic steatosis was based on the method described by Kleiner and on ...
متن کامل[Non-invasive evaluation of liver fibrosis in chronic hepatitis C].
Chronic hepatitis C (CHC) is a major public health concern, with around 180 million individuals affected worldwide. Liver fibrosis and its end-point cirrhosis are the main causes of morbidity and mortality in patients with CHC. Liver biopsy (LB) has traditionally been considered the "gold standard" for pre-treatment evaluation of liver fibrossis in patients with CHC. However, LB is an invasive ...
متن کاملFibrosis progression in chronic hepatitis C virus infection.
Chronic hepatitis C virus infection is typically characterised by slowly progressive hepatic fibrosis. However, it is recognised that some patients do not progress while others rapidly develop significant fibrosis. Here, we review studies that have assessed factors that could influence this rate of fibrotic progression.
متن کاملHepatitis C and fibrosis.
Hepatitis C virus (HCV) infection is a health problem involving more than 100 million people worldwide. However, despite these high numbers, only a group of infected people will develop serious difficulties from viral persistence. Liver fibrosis is the main complication of chronic HCV infection, and its eventual outcome –liver cirrhosis– is responsible for liver-related morbidity and mortality ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 2012
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.1212048109